• Product NameBLM Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total BLM protein.
• Immunogen Typepeptide
• Immunogen DescriptionSynthetic peptide of human BLM
• Target NameBLM
• Alternative Names    BS; RECQ2; RECQL2; RECQL3
• Accession No. Swiss-Prot#: P54132
  NCBI Gene ID: 641
• UniprotP54132
• Gene ID641;
• Concentration 0.8mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1: 20-100

The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination.

• The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using BLM Antibody at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200)

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting