EEPD1(endonuclease/exonuclease/phosphatase family domain containing 1), also known as HSPC107, is a 569 amino acid protein that contains one HhH domain. A significant decrease in the relative transcriptional level of EEPD1 is induced by long-term heat stress exposure. Conversely, EEPD1 is up-regulated in bovine adipogenic processes related to intramuscular pre-adipocyte differentiation. Encoded by a gene that maps to human chromosome 7p14.2, EEPD1 plays a role in DNA binding and repair. Chromosome 7 makes up about 5% of the human genome and contains 158 million bases encoding more than 1,000 genes. Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome are associated with Chromosome 7.
