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CDK1/CDC2 (Phospho-Thr161) Antibody #12493

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Catalog No. Package Size Price Quantity
50ul $219.00
100ul $319.00
Availability:Yes
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Description
  • Product NameCDK1/CDC2 (Phospho-Thr161) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • ApplicationsWB
  • Species ReactivityHu Ms Rt
  • SpecificityCDK1/CDC2 (Phospho-Thr161) Antibody detects endogenous levels of CDK1/CDC2 only when phosphorylated at Thr161
  • Immunogen TypePeptide
  • Immunogen DescriptionA synthesized peptide derived from human CDK1/CDC2 (Phospho-Thr161)
  • Target NameCDK1/CDC2
  • ModificationPhospho
  • Alternative Names    CDK1, CDC28A, CDC2, CDKN1, Cyclin-dependent kinase 1, p34 protein kinase, p34CDC2, CDC2a, Cell cycle controller CDC2, Cell division protein kinase 1, PSTAIR
  • Accession No. Swiss-Prot#: P06493
    NCBI Gene ID: 983
  • UniprotP06493
  • Gene ID983;
  • Target Species human
  • Calculated MW 34kd
  • Concentration 1.0mg/ml
  • Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20˚C
Application Details

Published Papers

Pseudolaric acid B induces mitotic arrest and apoptosis in both imatinib-sensitive and -resistant chronic myeloid leukaemia cells.In Eur J Pharmacol on 2020 Jun 5; by Jiang L, Wen C, et al..PMID: 32179085, , (2020),
PMID: 32179085
Pseudolaric acid B induces mitotic arrest and apoptosis in both 5-fluorouracil-sensitive and-resistant colorectal cancer cells.In Cancer Lett on 2016 Dec 28 by Chuangyu Wen , Junxiong Chen et al..PMID: 27713084, , (2016),
PMID: 27713084
Growth suppression and mitotic defect induced by JNJ-7706621, an inhibitor of cyclin-dependent kinases and aurora kinases. In Curr Cancer Drug Targets on 2012 Jul by A Matsuhashi, T Ohno, et al..PMID:22463590, , (2012),
PMID: 22463590
Please let us know if you have published research using #12493 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep