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NDR1/2 (Phospho-Thr444/442) Antibody #12521

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Catalog No. Package Size Price Quantity
50ul $265.00
100ul $439.00
Availability:Yes
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Description
  • Product NameNDR1/2 (Phospho-Thr444/442) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • ApplicationsWB
  • Species ReactivityHu Ms Rt
  • SpecificityNDR1/2 (Phospho-Thr444/442) Antibody detects endogenous levels of NDR1/2 only when phosphorylated at Thr444/442
  • Immunogen TypePeptide
  • Immunogen DescriptionA synthesized peptide derived from human NDR1/2 (Phospho-Thr444/442)
  • Target NameNDR1/2
  • ModificationPhospho
  • Alternative Names    STK38, NDR1 protein kinase, Nuclear Dbf2-related kinase 1, NDR1, NDR, Ndr protein kinase, Nuclear Dbf2-related 1, Serine/threonine kinase 38
  • Accession No. Swiss-Prot#: Q15208/Q9Y2H1
    NCBI Gene ID: 11329/23012
  • UniprotQ15208
  • Gene ID11329;
  • Target Species human
  • Calculated MW 54kd
  • Concentration 1.0mg/ml
  • Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20˚C
Application Details

Published Papers

Microautophagy regulated by STK38 and GABARAPs is essential to repair lysosomes and prevent aging In EMBO RepOn2023 Dec 6byMonami Ogura , Tatsuya Kaminishi et al..PMID:37987447, , (2023),
PMID: 37987447
NDR1 increases NOTCH1 signaling activity by impairing Fbw7 mediated NICD degradation to enhance breast cancer stem cell properties.In Mol Med. 2022 May 4 by Ling-Ling Wang, Xiao-Yun Wan, et al..PMID:35508987, , (2022),
PMID: 35508987
Prevention of calpaIn-dependent degradation of STK38 by MEKK2-mediated phosphorylation. In Sci Rep on 2019 Nov 5 by Enomoto A, Fukasawa T,et al..PMID:31690749, , (2019),
PMID: 31690749
Please let us know if you have published research using #12521 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep