• Product NameRb(Phospho-S807) Conjugated Antibody
• Host SpeciesRabbit
• ClonalityMonoclonal
• Species ReactivityHu, Ms, Rt
• Immunogen DescriptionSynthetic phospho-peptide corresponding to residues surrounding Ser380 of human RSK1.
• ConjugatesBiotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
• Excitation EmissionAF350: 346nm/442nm
  AF405: 401nm/421nm
  AF488: 493nm/519nm
  AF555: 555nm/565nm
  AF594: 591nm/614nm
  AF647: 651nm/667nm
  AF680: 679nm/702nm
  AF750: 749nm/775nm
• Alternative Names    90 kDa ribosomal protein S6 kinase 1 antibody
  dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1 antibody
  dJ590P13.1 antibody
  EC 2.7.11.1 antibody
  HU 1 antibody
  HU1 antibody
  KS6A1_HUMAN antibody
  MAP kinase activated protein kinase 1a antibody
  MAP kinase-activated protein kinase 1a antibody
  MAPK-activated protein kinase 1a antibody
  MAPKAP kinase 1a antibody
  MAPKAPK-1a antibody
  MAPKAPK1A antibody
  MGC79981 antibody
  Mitogen-activated protein kinase-activated protein kinase 1A antibody
  OTTHUMP00000004113 antibody
  p90 RSK1 antibody
  p90-RSK 1 antibody
  p90rsk antibody
  p90RSK1 antibody
  p90S6K antibody
  pp90RSK1 antibody
  Ribosomal protein S6 kinase 90kD 1 antibody
  Ribosomal protein S6 kinase 90kD polypeptide 1 antibody
  Ribosomal protein S6 kinase 90kDa polypeptide 1 antibody
  Ribosomal protein S6 kinase alpha 1 antibody
  Ribosomal protein S6 kinase alpha-1 antibody
  Ribosomal protein S6 kinase polypeptide 1 antibody
  Ribosomal S6 kinase 1 antibody
  RPS6K1 alpha antibody
  rps6ka antibody
  Rps6ka1 antibody
  RSK 1 antibody
  RSK 1 p90 antibody
  RSK antibody
  RSK-1 antibody
  RSK1 antibody
  S6K alpha 1 antibody
  S6K-alpha-1 antibody
  
• Accession No. Swiss-Prot#:Q15418
  
• UniprotQ15418
• Gene ID6195;
• Calculated MW 90
• Formulation 0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
• Storage Store at 4˚C in dark for 6 months

• Suggested Dilution:
  AF350 conjugated: most applications: 1: 50 - 1: 250
  AF405 conjugated: most applications: 1: 50 - 1: 250
  AF488 conjugated: most applications: 1: 50 - 1: 250
  AF555 conjugated: most applications: 1: 50 - 1: 250
  AF594 conjugated: most applications: 1: 50 - 1: 250
  AF647 conjugated: most applications: 1: 50 - 1: 250
  AF680 conjugated: most applications: 1: 50 - 1: 250
  AF750 conjugated: most applications: 1: 50 - 1: 250
  Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

The family of ribosomal S6 kinases (Rsks), designated Rsk-1, Rsk-2 and Rsk-3, are important signaling intermediates that mediate responses to a broad range of ligand-activated receptor tyrosine kinases. It has been established that Rsk-3 is not activated by MAP kinase in vitro, unlike Rsk-1 and Rsk-2. A unique feature common to the three members of the Rsk family is that each possesses two non-identical complete kinase catalytic domains. The Rsk family amino-terminal kinase domain is phosphorylated on Ser 227 by 3-phosphoinositide-dependent protein kinase-1 (PDK1), which increases the kinase activity of Rsk. In the carboxy-terminal kinase domain, Rsk-1 and Rsk-2 are autophosphorylated on Ser 380 and Ser 386, respectively, which mediates the docking of PDK1 to Rsk in order to promote phosphorylation of substrates, such as histone H3.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting