• Product NameAmyloid Beta A4 Precursor (APP) Conjugated Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• Species ReactivityHu,Ms,Rt
• Immunogen Descriptionpeptide
• ConjugatesBiotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
• Excitation EmissionAF350: 346nm/442nm
  AF405: 401nm/421nm
  AF488: 493nm/519nm
  AF555: 555nm/565nm
  AF594: 591nm/614nm
  AF647: 651nm/667nm
  AF680: 679nm/702nm
  AF750: 749nm/775nm
• Alternative Names    A4 amyloid protein antibody
  A4_HUMAN antibody
  AAA antibody
  ABETA antibody
  ABPP antibody
  AD1 antibody
  AICD-50 antibody
  AICD-57 antibody
  AICD-59 antibody
  AID(50) antibody
  AID(57) antibody
  AID(59) antibody
  Alzheimer disease amyloid protein antibody
  Amyloid beta (A4) precursor protein antibody
  Amyloid beta A4 protein antibody
  Amyloid beta protein antibody
  Amyloid intracellular domain 50 antibody
  Amyloid intracellular domain 57 antibody
  Amyloid intracellular domain 59 antibody
  Amyloid precursor protein antibody
  APP antibody
  APPI antibody
  Beta amyloid peptide antibody
  Beta-amyloid precursor protein antibody
  Beta-APP40 antibody
  Beta-APP42 antibody
  C31 antibody
  Cerebral vascular amyloid peptide antibody
  CTFgamma antibody
  CVAP antibody
  Gamma-CTF(50) antibody
  Gamma-CTF(57) antibody
  Gamma-CTF(59) antibody
  peptidase nexin II antibody
  PN 2 antibody
  PN II antibody
  PN-II antibody
  PN2 antibody
  PreA4 antibody
  Protease nexin II antibody
  Protease nexin-II antibody
  S-APP-alpha antibody
  S-APP-beta antibody
  
• Accession No. Swiss-Prot#:P05067
  
• UniprotP05067
• Gene ID351;
• Calculated MW 110 kDa
• Formulation 0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
• Storage Store at 4˚C in dark for 6 months

• Suggested Dilution:
  AF350 conjugated: most applications: 1: 50 - 1: 250
  AF405 conjugated: most applications: 1: 50 - 1: 250
  AF488 conjugated: most applications: 1: 50 - 1: 250
  AF555 conjugated: most applications: 1: 50 - 1: 250
  AF594 conjugated: most applications: 1: 50 - 1: 250
  AF647 conjugated: most applications: 1: 50 - 1: 250
  AF680 conjugated: most applications: 1: 50 - 1: 250
  AF750 conjugated: most applications: 1: 50 - 1: 250
  Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

Amyloid beta precursor protein (APP) is a 100-140 kDa transmembrane glycoprotein existing as several isoforms. The amino acid sequence of APP contains the amyloid domain (A-beta), which can be released by a two-step proteolytic cleavage. It is expressed in all fetal tissues examined with highest levels in brain, kidney, heart and spleen. APP acts as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. It is also involved in cell mobility and transcription regulation through protein-protein interactions.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting