• Product NameEstrogen Receptor alpha Conjugated Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• Species ReactivityHu, Baboon
• Immunogen Descriptionpeptide
• ConjugatesBiotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
• Excitation EmissionAF350: 346nm/442nm
  AF405: 401nm/421nm
  AF488: 493nm/519nm
  AF555: 555nm/565nm
  AF594: 591nm/614nm
  AF647: 651nm/667nm
  AF680: 679nm/702nm
  AF750: 749nm/775nm
• Alternative Names    DKFZp686N23123 antibody
  ER alpha antibody
  ER antibody
  ER-alpha antibody
  Era antibody
  ESR antibody
  ESR1 antibody
  ESR1_HUMAN antibody
  ESRA antibody
  Estradiol receptor antibody
  Estrogen nuclear receptor alpha antibody
  Estrogen receptor 1 antibody
  Estrogen receptor alpha 3*,4,5,6,7*/822 isoform antibody
  Estrogen receptor alpha antibody
  Estrogen receptor alpha delta 3*,4,5,6,7*,8*/941 isoform antibody
  Estrogen receptor alpha delta 3*,4,5,6,7*/819 2 isoform antibody
  Estrogen receptor alpha delta 4 +49 isoform antibody
  Estrogen receptor alpha delta 4*,5,6,7*/654 isoform antibody
  Estrogen receptor alpha delta 4*,5,6,7,8*/901 isoform antibody
  Estrogen receptor alpha E1 E2 1 2 antibody
  Estrogen receptor alpha E1 N2 E2 1 2 antibody
  Estrogen receptor antibody
  ESTRR antibody
  NR3A1 antibody
  Nuclear receptor subfamily 3 group A member 1 antibody
  
• Accession No. Swiss-Prot#:P03372
  
• UniprotP03372
• Gene ID2099;
• Calculated MW 66 kDa
• Formulation 0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
• Storage Store at 4˚C in dark for 6 months

• Suggested Dilution:
  AF350 conjugated: most applications: 1: 50 - 1: 250
  AF405 conjugated: most applications: 1: 50 - 1: 250
  AF488 conjugated: most applications: 1: 50 - 1: 250
  AF555 conjugated: most applications: 1: 50 - 1: 250
  AF594 conjugated: most applications: 1: 50 - 1: 250
  AF647 conjugated: most applications: 1: 50 - 1: 250
  AF680 conjugated: most applications: 1: 50 - 1: 250
  AF750 conjugated: most applications: 1: 50 - 1: 250
  Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

Estrogen receptor alpha (ER alpha) is a nuclear protein and member of the steroid hormone receptor family. ER alpha possesses both DNA binding and ligand binding domains, and exerts a significant role in activating the transcription of certain genes (1). Ligand-dependent dimerization and phosphorylation both function to regulate the transcriptional activation of ER alpha (2). The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy (3).

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting