• Product NameTGF-Beta 1 Conjugated Antibody
• Host SpeciesRabbit
• ClonalityMonoclonal
• Species ReactivityHu, Ms, Rt
• Immunogen Descriptionpeptide
• ConjugatesBiotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
• Excitation EmissionAF350: 346nm/442nm
  AF405: 401nm/421nm
  AF488: 493nm/519nm
  AF555: 555nm/565nm
  AF594: 591nm/614nm
  AF647: 651nm/667nm
  AF680: 679nm/702nm
  AF750: 749nm/775nm
• Alternative Names    Cartilage-inducing factor antibody
  CED antibody
  Differentiation inhibiting factor antibody
  DPD1 antibody
  LAP antibody
  Latency-associated peptide antibody
  Prepro transforming growth factor beta 1 antibody
  TGF beta 1 antibody
  TGF beta antibody
  TGF beta 1 protein antibody
  TGF-beta 1 protein antibody
  TGF-beta-1 antibody
  TGF-beta-5 antibody
  TGF-beta1 antibody
  TGFB antibody
  Tgfb-1 antibody
  tgfb1 antibody
  TGFB1_HUMAN antibody
  TGFbeta antibody
  TGFbeta1 antibody
  Transforming Growth Factor b1 antibody
  Transforming Growth Factor beta 1 antibody
  Transforming growth factor beta 1a antibody
  transforming growth factor beta-1 antibody
  transforming growth factor, beta 1 antibody
  Transforming Growth Factor-?1 antibody
  
• Accession No. Swiss-Prot#:P01137
  
• UniprotP01137
• Gene ID7040;
• Calculated MW 44 kDa
• Formulation 0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
• Storage Store at 4˚C in dark for 6 months

• Suggested Dilution:
  AF350 conjugated: most applications: 1: 50 - 1: 250
  AF405 conjugated: most applications: 1: 50 - 1: 250
  AF488 conjugated: most applications: 1: 50 - 1: 250
  AF555 conjugated: most applications: 1: 50 - 1: 250
  AF594 conjugated: most applications: 1: 50 - 1: 250
  AF647 conjugated: most applications: 1: 50 - 1: 250
  AF680 conjugated: most applications: 1: 50 - 1: 250
  AF750 conjugated: most applications: 1: 50 - 1: 250
  Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Heterodimers of TGFB1/TGFB2 have been found in bone. Interacts with CD109 and DPT. Interacts with ASPN. Function: TGF beta 2 has suppressive effects on interleukin-2 dependent T-cell growth. Tissue specificity: TGF beta 1 is highly expressed in bone. A chromosomal aberration involving TGFB2 is found in a family with Peters anomaly.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting