• Product NamePI 3 Kinase catalytic subunit alpha Conjugated Antibody
• Host SpeciesRabbit
• ClonalityMonoclonal
• Species ReactivityHu, Ms
• Immunogen Descriptionrecombinant protein
• ConjugatesBiotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
• Excitation EmissionAF350: 346nm/442nm
  AF405: 401nm/421nm
  AF488: 493nm/519nm
  AF555: 555nm/565nm
  AF594: 591nm/614nm
  AF647: 651nm/667nm
  AF680: 679nm/702nm
  AF750: 749nm/775nm
• Alternative Names    5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha antibody
  5-bisphosphate 3-kinase catalytic subunit alpha isoform antibody
  caPI3K antibody
  CLOVE antibody
  CWS5 antibody
  MCAP antibody
  MCM antibody
  MCMTC antibody
  MGC142161 antibody
  MGC142163 antibody
  p110 alpha antibody
  p110alpha antibody
  Phosphatidylinositol 3 kinase catalytic alpha polypeptide antibody
  Phosphatidylinositol 3 kinase catalytic 110 KD alpha antibody
  Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit alpha antibody
  Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit alpha isoform antibody
  Phosphatidylinositol 4,5 bisphosphate 3 kinase 110 kDa catalytic subunit alpha antibody
  Phosphatidylinositol-4 antibody
  Phosphoinositide 3 kinase catalytic alpha polypeptide antibody
  PI3 kinase p110 subunit alpha antibody
  PI3-kinase subunit alpha antibody
  PI3K antibody
  PI3K-alpha antibody
  PI3KC A antibody
  PIK3C A antibody
  Pik3ca antibody
  PK3CA antibody
  PK3CA_HUMAN antibody
  PtdIns 3 kinase p110 antibody
  PtdIns-3-kinase subunit alpha antibody
  PtdIns-3-kinase subunit p110-alpha antibody
  Serine/threonine protein kinase PIK3CA antibody
  
• Accession No. Swiss-Prot#:P42336
  
• UniprotP42336
• Gene ID5290;
• Calculated MW 124 kDa
• Formulation 0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
• Storage Store at 4˚C in dark for 6 months

• Suggested Dilution:
  AF350 conjugated: most applications: 1: 50 - 1: 250
  AF405 conjugated: most applications: 1: 50 - 1: 250
  AF488 conjugated: most applications: 1: 50 - 1: 250
  AF555 conjugated: most applications: 1: 50 - 1: 250
  AF594 conjugated: most applications: 1: 50 - 1: 250
  AF647 conjugated: most applications: 1: 50 - 1: 250
  AF680 conjugated: most applications: 1: 50 - 1: 250
  AF750 conjugated: most applications: 1: 50 - 1: 250
  Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

Phosphatidylinositol 3-kinase (PI 3-kinase) is composed of p85 and p110 subunits. p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85α and p85β), each possessing one SH3 and two SH2 domains. Various p110 isoforms have been identified. p110α and p110β interact with p85α, and p110α has also been shown to interact with p85β in vitro. p110δ expression is restricted to white blood cells. It has been shown to bind p85α and β, but it apparently does not phosphorylate these subunits. p110δ seems to have the capacity to autophosphorylate. p110γ does not interact with the p85 subunits. It has been shown to be activated by α and βγ heterotrimeric G proteins.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting