• Product NameMEK3+MEK6 Conjugated Antibody
• Host SpeciesRabbit
• ClonalityMonoclonal
• Species ReactivityHu, Ms, Rt
• Immunogen Descriptionrecombinant protein
• ConjugatesBiotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
• Excitation EmissionAF350: 346nm/442nm
  AF405: 401nm/421nm
  AF488: 493nm/519nm
  AF555: 555nm/565nm
  AF594: 591nm/614nm
  AF647: 651nm/667nm
  AF680: 679nm/702nm
  AF750: 749nm/775nm
• Alternative Names    Dual specificity mitogen activated protein kinase kinase 6 antibody
  Dual specificity mitogen-activated protein kinase kinase 3 antibody
  MAP kinase kinase 3 antibody
  MAP kinase kinase 6 antibody
  map2k3 antibody
  MAP2K6 antibody
  MAPK/ERK kinase 3 antibody
  MAPK/ERK kinase 6 antibody
  MAPKK 3 antibody
  MAPKK 6 antibody
  MAPKK3 antibody
  MAPKK6 antibody
  MEK 3 antibody
  MEK 6 antibody
  Mitogen activated protein kinase kinase 3 antibody
  Mitogen activated protein kinase kinase 6 antibody
  MKK3 antibody
  MKK6 antibody
  MP2K3_HUMAN antibody
  PRKMK3 antibody
  PRKMK6 antibody
  Protein kinase, mitogen activated, kinase 6 (MAP kinase kinase 6) antibody
  SAPK kinase 2 antibody
  SAPKK 3 antibody
  SAPKK-2 antibody
  SAPKK2 antibody
  SAPKK3 antibody
  Stress activated protein kinase kinase 3 antibody
  Stress-activated protein kinase kinase 2 antibody
  
• Accession No. Swiss-Prot#:P46734
  
• UniprotP46734
• Gene ID5606;
• Calculated MW 39/37 kDa
• Formulation 0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
• Storage Store at 4˚C in dark for 6 months

• Suggested Dilution:
  AF350 conjugated: most applications: 1: 50 - 1: 250
  AF405 conjugated: most applications: 1: 50 - 1: 250
  AF488 conjugated: most applications: 1: 50 - 1: 250
  AF555 conjugated: most applications: 1: 50 - 1: 250
  AF594 conjugated: most applications: 1: 50 - 1: 250
  AF647 conjugated: most applications: 1: 50 - 1: 250
  AF680 conjugated: most applications: 1: 50 - 1: 250
  AF750 conjugated: most applications: 1: 50 - 1: 250
  Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

A family of protein kinases located upstream of the MAP kinases and responsible for their activation has been identified. The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK5, whereas MEK-6 phosphorylates p38 and p38b. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting