• Product NameRac1-2-3 Conjugated Antibody
• Host SpeciesRabbit
• ClonalityMonoclonal
• Species ReactivityHu, Ms, Rt
• Immunogen Descriptionrecombinant protein
• ConjugatesBiotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
• Excitation EmissionAF350: 346nm/442nm
  AF405: 401nm/421nm
  AF488: 493nm/519nm
  AF555: 555nm/565nm
  AF594: 591nm/614nm
  AF647: 651nm/667nm
  AF680: 679nm/702nm
  AF750: 749nm/775nm
• Alternative Names    Cell migration inducing gene 5 protein antibody
  EN 7 antibody
  OTTMUSP00000004488 antibody
  p21 Rac3 antibody
  p21-Rac3 antibody
  Rac1B antibody
  RAC3 antibody
  RAC3_HUMAN antibody
  RAS related C3 botulinum substrate 3 antibody
  Ras related C3 botulinum toxin substrate 3 (rho family small GTP binding protein Rac3) antibody
  Ras related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) antibody
  Ras-related C3 botulinum toxin substrate 3 antibody
  Rho family small GTP binding protein Rac3 antibody
  RP23-84C12.18 antibody
  EN-7 antibody
  EN7 antibody
  GX antibody
  HSPC 022 antibody
  HSPC022 antibody
  p21 Rac 2 antibody
  p21 Rac2 antibody
  p21-Rac2 antibody
  p21Rac2 antibody
  RAC 2 antibody
  Rac2 antibody
  RAC2_HUMAN antibody
  Ras related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2 antibody
  Ras related C3 botulinum toxin substrate 2 antibody
  Ras related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac2) antibody
  Ras related C3 botulinum toxin substrate 3 antibody
  Ras-related C3 botulinum toxin substrate 2 antibody
  Rho family small GTP binding protein Rac 2 antibody
  Rho family small GTP binding protein Rac2 antibody
  Small G protein antibody
  Cell migration-inducing gene 5 protein antibody
  MGC111543 antibody
  MIG5 antibody
  Migration inducing gene 5 antibody
  Migration inducing protein 5 antibody
  p21 Rac1 antibody
  p21-Rac1 antibody
  Rac 1 antibody
  RAC1 antibody
  RAC1_HUMAN antibody
  Ras like protein TC25 antibody
  Ras related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) antibody
  Ras-like protein TC25 antibody
  Ras-related C3 botulinum toxin substrate 1 antibody
  Rho family small GTP binding protein Rac1 antibody
  TC 25 antibody
  TC25 antibody
  
• Accession No. Swiss-Prot#:P63000
  
• UniprotP63000
• Gene ID5879;
• Calculated MW 21/24 kDa
• Formulation 0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
• Storage Store at 4˚C in dark for 6 months

• Suggested Dilution:
  AF350 conjugated: most applications: 1: 50 - 1: 250
  AF405 conjugated: most applications: 1: 50 - 1: 250
  AF488 conjugated: most applications: 1: 50 - 1: 250
  AF555 conjugated: most applications: 1: 50 - 1: 250
  AF594 conjugated: most applications: 1: 50 - 1: 250
  AF647 conjugated: most applications: 1: 50 - 1: 250
  AF680 conjugated: most applications: 1: 50 - 1: 250
  AF750 conjugated: most applications: 1: 50 - 1: 250
  Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity in macrophages (By similarity). Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. Isoform B has an accelerated GEF-independent GDP/GTP exchange and an impaired GTP hydrolysis, which is restored partially by GTPase-activating proteins. It is able to bind to the GTPase-binding domain of PAK but not full-length PAK in a GTP-dependent manner, suggesting that the insertion does not completely abolish effector interaction.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting