• Product NameIP3 Receptor Conjugated Antibody
• Host SpeciesRabbit
• ClonalityMonoclonal
• Species ReactivityHu, Ms, Rt
• Immunogen Descriptionrecombinant protein
• ConjugatesBiotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
• Excitation EmissionAF350: 346nm/442nm
  AF405: 401nm/421nm
  AF488: 493nm/519nm
  AF555: 555nm/565nm
  AF594: 591nm/614nm
  AF647: 651nm/667nm
  AF680: 679nm/702nm
  AF750: 749nm/775nm
• Alternative Names    4 antibody
  5-trisphosphate receptor antibody
  5-trisphosphate receptor type 1 antibody
  DKFZp313E1334 antibody
  DKFZp313N1434 antibody
  inositol 1 4 5 triphosphate receptor type 1 antibody
  Inositol 1 4 5 trisphosphate Receptor Type 1 antibody
  Inositol 1 antibody
  InsP3R1 antibody
  IP3 antibody
  IP3 receptor antibody
  IP3 receptor isoform 1 antibody
  IP3R 1 antibody
  IP3R antibody
  IP3R1 antibody
  ITPR 1 antibody
  Itpr1 antibody
  ITPR1_HUMAN antibody
  SCA15 antibody
  SCA16 antibody
  SCA29 antibody
  Type 1 inositol 1 4 5 trisphosphate receptor antibody
  Type 1 inositol 1 antibody
  Type 1 InsP3 receptor antibody
  
• Accession No. Swiss-Prot#:Q14643
  
• UniprotQ14643
• Gene ID3708;
• Calculated MW 314 kDa
• Formulation 0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
• Storage Store at 4˚C in dark for 6 months

• Suggested Dilution:
  AF350 conjugated: most applications: 1: 50 - 1: 250
  AF405 conjugated: most applications: 1: 50 - 1: 250
  AF488 conjugated: most applications: 1: 50 - 1: 250
  AF555 conjugated: most applications: 1: 50 - 1: 250
  AF594 conjugated: most applications: 1: 50 - 1: 250
  AF647 conjugated: most applications: 1: 50 - 1: 250
  AF680 conjugated: most applications: 1: 50 - 1: 250
  AF750 conjugated: most applications: 1: 50 - 1: 250
  Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting