• Product NameCytochrome P450 3A4 Conjugated Antibody
• Host SpeciesRabbit
• ClonalityMonoclonal
• Species ReactivityHu
• Immunogen Descriptionrecombinant protein
• ConjugatesBiotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
• Excitation EmissionAF350: 346nm/442nm
  AF405: 401nm/421nm
  AF488: 493nm/519nm
  AF555: 555nm/565nm
  AF594: 591nm/614nm
  AF647: 651nm/667nm
  AF680: 679nm/702nm
  AF750: 749nm/775nm
• Alternative Names    1,8-cineole 2-exo-monooxygenase antibody
  Albendazole monooxygenase antibody
  Albendazole sulfoxidase antibody
  CP33 antibody
  CP34 antibody
  CP3A4_HUMAN antibody
  CYP3 antibody
  CYP3A antibody
  CYP3A3 antibody
  CYP3A4 antibody
  CYPIIIA3 antibody
  CYPIIIA4 antibody
  Cytochrome P450 3A3 antibody
  Cytochrome P450 3A4 antibody
  Cytochrome P450 family 3 subfamily A polypeptide 4 antibody
  Cytochrome P450 HLp antibody
  Cytochrome P450 NF-25 antibody
  Cytochrome P450 subfamily IIIA polypeptide 4 antibody
  cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3 antibody
  cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 antibody
  Cytochrome P450-PCN1 antibody
  Glucocorticoid inducible P450 antibody
  HLP antibody
  MGC126680 antibody
  NF 25 antibody
  NF25 antibody
  Nifedipine oxidase antibody
  P450 III steroid inducible antibody
  P450 PCN1 antibody
  P450, family III antibody
  P450C3 antibody
  P450PCN1 antibody
  Quinine 3 monooxygenase antibody
  Quinine 3-monooxygenase antibody
  Taurochenodeoxycholate 6 alpha hydroxylase antibody
  Taurochenodeoxycholate 6-alpha-hydroxylase antibody
  
• Accession No. Swiss-Prot#:P08684
  
• UniprotP08684
• Gene ID1576;
• Calculated MW 57 kDa
• Formulation 0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
• Storage Store at 4˚C in dark for 6 months

• Suggested Dilution:
  AF350 conjugated: most applications: 1: 50 - 1: 250
  AF405 conjugated: most applications: 1: 50 - 1: 250
  AF488 conjugated: most applications: 1: 50 - 1: 250
  AF555 conjugated: most applications: 1: 50 - 1: 250
  AF594 conjugated: most applications: 1: 50 - 1: 250
  AF647 conjugated: most applications: 1: 50 - 1: 250
  AF680 conjugated: most applications: 1: 50 - 1: 250
  AF750 conjugated: most applications: 1: 50 - 1: 250
  Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

CYP3A, the most abundant p450 enzyme in human liver, is responsible for the metabolism of more than 50% of the clinical test & lt; RTI ID = 0.0 & gt; (cYP3A) genes encode monooxygenases-enzymes which catalyze drug metabolism and the synthesis of cholesterol, steroids and other lipids. CYP3A family members localize in organs that associate with drug disposition, including the liver, gastrointestinal tract and kidney. The CYP3A cluster maps to gene locus 7q22.1 and consists of four genes (CYP3A4, CYP3A5, CYP3A7 and CYP3A43) and two pseudogenes ( CYP3A4 is abundant in the endoplasmic reticulum of liver cells and upper intestinal enterocytes. CYP3A4 expression is isducible by glucocorticoids pharmacological agents.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting