• Product NameNogo B Conjugated Antibody
• Host SpeciesRabbit
• ClonalityMonoclonal
• Species ReactivityHu, Ms
• Immunogen DescriptionRecombinant protein
• ConjugatesBiotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
• Excitation EmissionAF350: 346nm/442nm
  AF405: 401nm/421nm
  AF488: 493nm/519nm
  AF555: 555nm/565nm
  AF594: 591nm/614nm
  AF647: 651nm/667nm
  AF680: 679nm/702nm
  AF750: 749nm/775nm
• Alternative Names    1110020G17Rik antibody
  AA407876 antibody
  AA409940 antibody
  AA960376 antibody
  ASY antibody
  C130026I10Rik antibody
  Foocen antibody
  Glut4 vesicle 20 kDa protein antibody
  Human NogoA antibody
  Kiaa0886 antibody
  KIAA4153 antibody
  MGC116054 antibody
  MGC139261 antibody
  mKIAA0886 antibody
  mKIAA4153 antibody
  My043 protein antibody
  Nbla00271 antibody
  Nbla10545 antibody
  Neurite growth inhibitor 220 antibody
  Neurite Growth Inhibitor 220, included antibody
  Neurite outgrowth inhibitor antibody
  Neuroendocrine-specific protein antibody
  Neuroendocrine-specific protein C homolog antibody
  NI-250 antibody
  NI220/250 antibody
  Nogo A antibody
  NOGO antibody
  Nogo B antibody
  Nogo C antibody
  Nogo protein antibody
  NOGOC antibody
  NSP antibody
  NSP-CL antibody
  rat N antibody
  Reticulon 4 antibody
  Reticulon 5 antibody
  Reticulon-4 antibody
  Reticulon-5 antibody
  RTN X antibody
  RTN-x antibody
  Rtn4 antibody
  Rtn4 reticulon 4 antibody
  RTN4-A antibody
  RTN4-B1 antibody
  RTN4-B2 antibody
  RTN4-C antibody
  RTN4_HUMAN antibody
  Vp20 antibody
  
• Accession No. Swiss-Prot#:Q9NQC3
  
• UniprotQ9NQC3
• Gene ID57142;
• Formulation 0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
• Storage Store at 4˚C in dark for 6 months

• Suggested Dilution:
  AF350 conjugated: most applications: 1: 50 - 1: 250
  AF405 conjugated: most applications: 1: 50 - 1: 250
  AF488 conjugated: most applications: 1: 50 - 1: 250
  AF555 conjugated: most applications: 1: 50 - 1: 250
  AF594 conjugated: most applications: 1: 50 - 1: 250
  AF647 conjugated: most applications: 1: 50 - 1: 250
  AF680 conjugated: most applications: 1: 50 - 1: 250
  AF750 conjugated: most applications: 1: 50 - 1: 250
  Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching. Regulates neurite fasciculation, branching and extension in the developing nervous system. Involved in down-regulation of growth, stabilization of wiring and restriction of plasticity in the adult CNS. Regulates the radial migration of cortical neurons via an RTN4R-LINGO1 containing receptor complex. Isoform 2 reduces the anti-apoptotic activity of Bcl-xl and Bcl-2. This is likely consecutive to their change in subcellular location, from the mitochondria to the endoplasmic reticulum, after binding and sequestration. Isoform 2 and isoform 3 inhibit BACE1 activity and amyloid precursor protein processing.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting