• Product NamePDX1 Conjugated Antibody
• Host SpeciesRabbit
• ClonalityMonoclonal
• Species ReactivityHu
• Immunogen DescriptionRecombinant protein
• ConjugatesBiotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
• Excitation EmissionAF350: 346nm/442nm
  AF405: 401nm/421nm
  AF488: 493nm/519nm
  AF555: 555nm/565nm
  AF594: 591nm/614nm
  AF647: 651nm/667nm
  AF680: 679nm/702nm
  AF750: 749nm/775nm
• Alternative Names    Glucose sensitive factor antibody
  Glucose-sensitive factor antibody
  GSF antibody
  IDX 1 antibody
  IDX-1 antibody
  IDX1 antibody
  Insulin promoter factor 1 antibody
  Insulin promoter factor 1 homeodomain transcription factor antibody
  Insulin upstream factor 1 antibody
  IPF 1 antibody
  IPF-1 antibody
  IPF1 antibody
  Islet/duodenum homeobox 1 antibody
  Islet/duodenum homeobox-1 antibody
  IUF 1 antibody
  IUF-1 antibody
  IUF1 antibody
  MODY4 antibody
  Pancreas/duodenum homeobox 1 antibody
  Pancreas/duodenum homeobox protein 1 antibody
  pancreatic and duodenal homeobox P antibody
  PDX 1 antibody
  PDX-1 antibody
  PDX1 antibody
  PDX1_HUMAN antibody
  Somatostatin transactivating factor 1 antibody
  Somatostatin-transactivating factor 1 antibody
  STF 1 antibody
  STF-1 antibody
  STF1 antibody
  
• Accession No. Swiss-Prot#:P52945
  
• UniprotP52945
• Gene ID3651;
• Formulation 0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
• Storage Store at 4˚C in dark for 6 months

• Suggested Dilution:
  AF350 conjugated: most applications: 1: 50 - 1: 250
  AF405 conjugated: most applications: 1: 50 - 1: 250
  AF488 conjugated: most applications: 1: 50 - 1: 250
  AF555 conjugated: most applications: 1: 50 - 1: 250
  AF594 conjugated: most applications: 1: 50 - 1: 250
  AF647 conjugated: most applications: 1: 50 - 1: 250
  AF680 conjugated: most applications: 1: 50 - 1: 250
  AF750 conjugated: most applications: 1: 50 - 1: 250
  Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

Activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. Particularly involved in glucose-dependent regulation of insulin gene transcription. Binds preferentially the DNA motif 5'-[CT]TAAT[TG]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, required for maintaining the hormone-producing phenotype of the beta-cell.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting