• Product NameCD11b Conjugated Antibody
• Host SpeciesRabbit
• ClonalityMonoclonal
• Species ReactivityHu
• Immunogen DescriptionRecombinant protein
• ConjugatesBiotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
• Excitation EmissionAF350: 346nm/442nm
  AF405: 401nm/421nm
  AF488: 493nm/519nm
  AF555: 555nm/565nm
  AF594: 591nm/614nm
  AF647: 651nm/667nm
  AF680: 679nm/702nm
  AF750: 749nm/775nm
• Alternative Names    antigen CD11b (p170) antibody
  Antigen CD11b p170 antibody
  CD11 antigen like family member B antibody
  CD11 antigen-like family member B antibody
  CD11b antibody
  CD11b/CD18 antibody
  CD49d antibody
  Cell surface glycoprotein MAC-1 subunit alpha antibody
  Complement component 3 receptor 3 subunit antibody
  Complement Component Receptor 3 Alpha antibody
  Complement receptor type 3, alpha subunit antibody
  CR 3 alpha chain (CR3A) antibody
  CR 3 alpha chain antibody
  CR-3 alpha chain antibody
  CR3 antibody
  CR3A antibody
  F730045J24Rik antibody
  Integrin Alpha M antibody
  Integrin alpha M chain antibody
  Integrin alpha-M antibody
  Integrin beta 2 alpha subunit antibody
  Integrin subunit alpha M antibody
  integrin, alpha M (complement component 3 receptor 3 subunit) antibody
  ITAM_HUMAN antibody
  ITGAM antibody
  Leukocyte adhesion receptor MO1 antibody
  Ly-40 antibody
  MAC 1 antibody
  Mac-1a antibody
  MAC1 antibody
  Mac1, alpha subunit antibody
  MAC1A antibody
  Macrophage antigen alpha polypeptide antibody
  MGC117044 antibody
  Mo1, alpha subunit antibody
  MO1A antibody
  Neutrophil adherence receptor alpha M subunit antibody
  Neutrophil adherence receptor antibody
  SLEB6 antibody
  
• Accession No. Swiss-Prot#:P11215
  
• UniprotP11215
• Gene ID3684;
• Calculated MW 170 kDa
• Formulation 0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
• Storage Store at 4˚C in dark for 6 months

• Suggested Dilution:
  AF350 conjugated: most applications: 1: 50 - 1: 250
  AF405 conjugated: most applications: 1: 50 - 1: 250
  AF488 conjugated: most applications: 1: 50 - 1: 250
  AF555 conjugated: most applications: 1: 50 - 1: 250
  AF594 conjugated: most applications: 1: 50 - 1: 250
  AF647 conjugated: most applications: 1: 50 - 1: 250
  AF680 conjugated: most applications: 1: 50 - 1: 250
  AF750 conjugated: most applications: 1: 50 - 1: 250
  Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

Integrin αM, also designated complement component receptor-3 α, CD11b (p170), macrophage antigen a polypeptide, cell surface glycoprotein Mac-1 a subunit, MAC1A, MO1A and ITGAM) is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin αM combines with the Integrin β2 to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin αM/β2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting