• Product NameHSD11B1 Conjugated Antibody
• Host SpeciesRabbit
• ClonalityMonoclonal
• Species ReactivityHu, Ms, Rt
• Immunogen DescriptionRecombinant protein
• ConjugatesBiotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
• Excitation EmissionAF350: 346nm/442nm
  AF405: 401nm/421nm
  AF488: 493nm/519nm
  AF555: 555nm/565nm
  AF594: 591nm/614nm
  AF647: 651nm/667nm
  AF680: 679nm/702nm
  AF750: 749nm/775nm
• Alternative Names    11 beta HSD 1 antibody
  11 beta HSD1 antibody
  11 beta hydroxysteroid dehydrogenase 1 antibody
  11 DH antibody
  11-beta hydroxysteroid dehydrogenase, type 1 antibody
  11-beta-HSD1 antibody
  11-beta-hydroxysteroid dehydrogenase 1 antibody
  11-DH antibody
  11DH antibody
  Corticosteroid 11 beta dehydrogenase isozyme 1 antibody
  Corticosteroid 11-beta-dehydrogenase isozyme 1 antibody
  CORTRD2 antibody
  DHI1_HUMAN antibody
  HDL antibody
  HSD 11 antibody
  HSD11 antibody
  HSD11B antibody
  HSD11B1 antibody
  HSD11L antibody
  Hydroxysteroid (11 beta) dehydrogenase antibody
  Hydroxysteroid (11 beta) dehydrogenase 1 antibody
  MGC13539 antibody
  SDR26C1 antibody
  short chain dehydrogenase/reductase family 26C, member 1 antibody
  
• Accession No. Swiss-Prot#:P28845
  
• UniprotP28845
• Gene ID3290;
• Calculated MW 32 kDa
• Formulation 0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
• Storage Store at 4˚C in dark for 6 months

• Suggested Dilution:
  AF350 conjugated: most applications: 1: 50 - 1: 250
  AF405 conjugated: most applications: 1: 50 - 1: 250
  AF488 conjugated: most applications: 1: 50 - 1: 250
  AF555 conjugated: most applications: 1: 50 - 1: 250
  AF594 conjugated: most applications: 1: 50 - 1: 250
  AF647 conjugated: most applications: 1: 50 - 1: 250
  AF680 conjugated: most applications: 1: 50 - 1: 250
  AF750 conjugated: most applications: 1: 50 - 1: 250
  Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

HSD11B1(Corticosteroid 11-beta-dehydrogenase isozyme 1) is also named as HSD11, HSD11L,11-DH and 11-beta-HSD1.It is a microsomal enzyme, which acts mainly as a NADP(H)- dependent reductase converting inactive cortisone (E) to active cortisol (F), thus regulating intracellular F access to glucocorticoid receptor. This enzyme is widely expressed not only in liver and adipose tissue, but also in adrenal, ovary and decidua.Western blot analysis in human liver, using a specific11-beta-HSD1 antibody, showed two bands at approximately 34 and 68 kDa confrming the dimeric nature of 11-beta-HSD1 in liver and In omental adipose tissue, an additional band of 50 kDa was strongly expressed.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting