• Product NamePTBP1 Conjugated Antibody
• Host SpeciesRabbit
• ClonalityMonoclonal
• Species ReactivityHu, Ms, Rt
• Immunogen DescriptionRecombinant protein
• ConjugatesBiotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
• Excitation EmissionAF350: 346nm/442nm
  AF405: 401nm/421nm
  AF488: 493nm/519nm
  AF555: 555nm/565nm
  AF594: 591nm/614nm
  AF647: 651nm/667nm
  AF680: 679nm/702nm
  AF750: 749nm/775nm
• Alternative Names    57 kDa RNA binding protein PPTB 1 antibody
  57 kDa RNA-binding protein PPTB-1 antibody
  Heterogeneous nuclear ribonucleoprotein I antibody
  Heterogeneous Nuclear Ribonucleoprotein Polypeptide I antibody
  hnRNP I antibody
  HNRNP-I antibody
  HNRNPI antibody
  HNRPI antibody
  MGC10830 antibody
  MGC8461 antibody
  Polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I) antibody
  Polypyrimidine Tract Binding Protein 1 antibody
  Polypyrimidine tract binding protein antibody
  Polypyrimidine tract-binding protein 1 antibody
  pPTB antibody
  PTB 1 antibody
  PTB 2 antibody
  PTB 3 antibody
  PTB 4 antibody
  PTB antibody
  PTB T antibody
  PTB1 antibody
  PTB2 antibody
  PTB3 antibody
  PTB4 antibody
  PTBP 1 antibody
  PTBP1 antibody
  PTBP1_HUMAN antibody
  PTBT antibody
  RNA Binding Protein antibody
  
• Accession No. Swiss-Prot#:P26599
  
• UniprotP26599
• Gene ID5725;
• Calculated MW 57 kDa
• Formulation 0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
• Storage Store at 4˚C in dark for 6 months

• Suggested Dilution:
  AF350 conjugated: most applications: 1: 50 - 1: 250
  AF405 conjugated: most applications: 1: 50 - 1: 250
  AF488 conjugated: most applications: 1: 50 - 1: 250
  AF555 conjugated: most applications: 1: 50 - 1: 250
  AF594 conjugated: most applications: 1: 50 - 1: 250
  AF647 conjugated: most applications: 1: 50 - 1: 250
  AF680 conjugated: most applications: 1: 50 - 1: 250
  AF750 conjugated: most applications: 1: 50 - 1: 250
  Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10. In case of infection by picornaviruses, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting