• Product NameAtg16L1 Conjugated Antibody
• Host SpeciesRabbit
• ClonalityMonoclonal
• Species ReactivityHu, Ms, Rt
• Immunogen DescriptionRecombinant protein
• ConjugatesBiotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
• Excitation EmissionAF350: 346nm/442nm
  AF405: 401nm/421nm
  AF488: 493nm/519nm
  AF555: 555nm/565nm
  AF594: 591nm/614nm
  AF647: 651nm/667nm
  AF680: 679nm/702nm
  AF750: 749nm/775nm
• Alternative Names    A16L1_HUMAN antibody
  APG16 like 1 antibody
  APG16-like 1 antibody
  APG16L antibody
  APG16L beta antibody
  ATG16 autophagy related 16 like 1 antibody
  ATG16 autophagy related 16-like 1 (S. cerevisiae) antibody
  ATG16A antibody
  ATG16L antibody
  Atg16l1 antibody
  Autophagy related protein 16 1 antibody
  Autophagy-related protein 16-1 antibody
  FLJ00045 antibody
  FLJ10035 antibody
  FLJ10828 antibody
  FLJ22677 antibody
  IBD10 antibody
  OTTHUMP00000164391 antibody
  OTTHUMP00000164393 antibody
  OTTHUMP00000165876 antibody
  OTTHUMP00000165877 antibody
  WD repeat domain 30 antibody
  WDR30 antibody
  
• Accession No. Swiss-Prot#:Q676U5
  
• UniprotQ676U5
• Gene ID55054;
• Calculated MW 68/66 kDa
• Formulation 0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
• Storage Store at 4˚C in dark for 6 months

• Suggested Dilution:
  AF350 conjugated: most applications: 1: 50 - 1: 250
  AF405 conjugated: most applications: 1: 50 - 1: 250
  AF488 conjugated: most applications: 1: 50 - 1: 250
  AF555 conjugated: most applications: 1: 50 - 1: 250
  AF594 conjugated: most applications: 1: 50 - 1: 250
  AF647 conjugated: most applications: 1: 50 - 1: 250
  AF680 conjugated: most applications: 1: 50 - 1: 250
  AF750 conjugated: most applications: 1: 50 - 1: 250
  Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane. Regulates mitochondrial antiviral signaling (MAVS)-dependent type I interferon (IFN-I) production. Negatively regulates NOD1- and NOD2-driven inflammatory cytokine response. Plays a role in regulating morphology and function of Paneth cell.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting