• Product NameMMP17 Conjugated Antibody
• Host SpeciesRabbit
• ClonalityMonoclonal
• Species ReactivityHu, Ms, Rt
• Immunogen DescriptionRecombinant protein within human MMP17 aa 1-250.
• ConjugatesBiotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
• Excitation EmissionAF350: 346nm/442nm
  AF405: 401nm/421nm
  AF488: 493nm/519nm
  AF555: 555nm/565nm
  AF594: 591nm/614nm
  AF647: 651nm/667nm
  AF680: 679nm/702nm
  AF750: 749nm/775nm
• Alternative Names    Matrix metalloproteinase 17 antibody
  Matrix metalloproteinase 17 membrane inserted antibody
  Matrix metalloproteinase-17 antibody
  Membrane type 4 matrix metalloproteinase antibody
  Membrane type matrix metalloproteinase 4 antibody
  Membrane-type matrix metalloproteinase 4 antibody
  Membrane-type-4 matrix metalloproteinase antibody
  MMP 17 antibody
  MMP-17 antibody
  Mmp17 antibody
  MMP17_HUMAN antibody
  MT MMP 4 antibody
  MT MMP4 antibody
  MT-MMP 4 antibody
  MT4 MMP antibody
  MT4-MMP antibody
  MT4MMP antibody
  MTMMP 4 antibody
  MTMMP4 antibody
  
• Accession No. Swiss-Prot#:Q9ULZ9
  
• UniprotQ9ULZ9
• Gene ID4326;
• Calculated MW 67 kDa
• Formulation 0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
• Storage Store at 4˚C in dark for 6 months

• Suggested Dilution:
  AF350 conjugated: most applications: 1: 50 - 1: 250
  AF405 conjugated: most applications: 1: 50 - 1: 250
  AF488 conjugated: most applications: 1: 50 - 1: 250
  AF555 conjugated: most applications: 1: 50 - 1: 250
  AF594 conjugated: most applications: 1: 50 - 1: 250
  AF647 conjugated: most applications: 1: 50 - 1: 250
  AF680 conjugated: most applications: 1: 50 - 1: 250
  AF750 conjugated: most applications: 1: 50 - 1: 250
  Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Cleaves pro-TNF-alpha at the '74-Ala-|-Gln-75' site. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting