• Product NameGemin 1 Conjugated Antibody
• Host SpeciesRabbit
• ClonalityMonoclonal
• Species ReactivityHu, Ms, Rt
• Immunogen DescriptionRecombinant protein within human Gemin 1 aa 1-200.
• ConjugatesBiotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
• Excitation EmissionAF350: 346nm/442nm
  AF405: 401nm/421nm
  AF488: 493nm/519nm
  AF555: 555nm/565nm
  AF594: 591nm/614nm
  AF647: 651nm/667nm
  AF680: 679nm/702nm
  AF750: 749nm/775nm
• Alternative Names    BCD541 antibody
  Component of gems 1 antibody
  Gemin 1 antibody
  Gemin-1 antibody
  OTTHUMP00000125198 antibody
  OTTHUMP00000223567 antibody
  OTTHUMP00000223568 antibody
  OTTHUMP00000224066 antibody
  OTTHUMP00000226924 antibody
  SMA 1 antibody
  SMA 2 antibody
  SMA 3 antibody
  SMA 4 antibody
  SMA antibody
  SMA@ antibody
  SMA1 antibody
  SMA2 antibody
  SMA3 antibody
  SMA4 antibody
  SMN antibody
  SMN_HUMAN antibody
  SMN1 antibody
  SMN2 antibody
  SMNT antibody
  Survival motor neuron protein antibody
  Survival of motor neuron 1, telomeric antibody
  T-BCD541 antibody
  
• Accession No. Swiss-Prot#:Q16637
  
• UniprotQ16637
• Gene ID6606;6607;
• Calculated MW 32 kDa
• Formulation 0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
• Storage Store at 4˚C in dark for 6 months

• Suggested Dilution:
  AF350 conjugated: most applications: 1: 50 - 1: 250
  AF405 conjugated: most applications: 1: 50 - 1: 250
  AF488 conjugated: most applications: 1: 50 - 1: 250
  AF555 conjugated: most applications: 1: 50 - 1: 250
  AF594 conjugated: most applications: 1: 50 - 1: 250
  AF647 conjugated: most applications: 1: 50 - 1: 250
  AF680 conjugated: most applications: 1: 50 - 1: 250
  AF750 conjugated: most applications: 1: 50 - 1: 250
  Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Ensures the correct splicing of U12 intron-containing genes that may be important for normal motor and proprioceptive neurons development. Also required for resolving RNA-DNA hybrids created by RNA polymerase II, that form R-loop in transcription terminal regions, an important step in proper transcription termination. May also play a role in the metabolism of small nucleolar ribonucleoprotein (snoRNPs).

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting