- Product NameProtease Inhibitor Library
- Brief DescriptionProtease inhibitorsaremoleculesthat inhibit the function ofproteases(enzymesthat aidthe breakdown of proteins), including proteins protease inhibitors, natural protease inhibitors, and synthetic protease inhibitors. (1). Antiprotozoal activity: protease inhibitors could be used against malaria and gastrointestinal protozoal infections; (2). Antiretrovirals: protease inhibitors were the second class of antiretroviral drugs developed widely used to treat HIV/AIDS and hepatitis C; (3). Anticancer activity: Researchers are investigating whether protease inhibitors could possibly be used to treat cancer. For example, nelfinavir and atazanavir are able to kill tumor cells in culture. Inhibitors of theproteasome, such asbortezomibare now front-line drugs for the treatment ofmultiple myeloma. Marimastat and batimastatare two of thematrix metalloproteinase inhibitorsthat can be used to treat cancer. The Protease Inhibitor Library by SAB, containing 162 small protease and proteasome inhibitors, can be used for research in Chemical Genomics and drug screening.
- Storage Powder or pre-dissolved DMSO solutions in 96 well plate with optional 2D barcodeShipped with blue ice; Stable for One year as powder, 6 months at - 20 ˚ C in DMSO or 12months at -80 ˚ C in DMSO
