- Product NameNuclear-receptor inhibitors library
- Brief DescriptionNuclear receptorsare a class ofproteins, different from membrane receptors located in the cell membrane,found within cells that are responsible for sensingsteroidandthyroidhormonesand certain other molecules.Nuclear receptors have the ability to directly bind toDNAand regulate the expression of adjacent genes, hence these receptors are classified astranscription factors, thereby controlling thedevelopment,homeostasis, andmetabolism of the organism. Over the last 15 years a growing number of nuclear receptors have been identified that coordinate genetic networks regulating lipid metabolism and energy utilization andunderlie the pathogenesis of metabolic diseases, such as obesity, type II diabetes, hypertension, and cardiovascular disease. SAB collects 239 reported compounds targeting nuclear receptors as Nuclear Receptor Compound Library, which can be used for research in nuclear receptor signaling and related diseases, and high throughput and high content screening for drug discovery
- Storage Powder or pre-dissolved DMSO solutions in 96 well plate with optional 2D barcodeShipped with dry ice
