• Product NameSMG6 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB
• Species ReactivityHuman,Rat
• Immunogen DescriptionRecombinant fusion protein of human SMG6 (NP_060045.4).
• Alternative Names    SMG6; C17orf31; EST1A; SMG-6; hSMG5/7a; telomerase-binding protein EST1A
• Accession No. Swiss-Prot#:Q86US8
  NCBI Gene ID:23293
• UniprotQ86US8
• Gene ID23293;
• Calculated MW 210kDa
• Formulation Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
• Storage Store at -20˚C

• WB 1:500 - 1:2000

This gene encodes a component of the telomerase ribonucleoprotein complex responsible for the replication and maintenance of chromosome ends. The encoded protein also plays a role in the nonsense-mediated mRNA decay (NMD) pathway, providing the endonuclease activity near the premature translation termination codon that is needed to initiate NMD. Alternatively spliced transcript variants encoding distinct protein isoforms have been described.

• Western blot analysis of extracts of various cell lines, using SMG6 at 1:1000 dilution.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting