• Product NameSPG7 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB,IHC
• Species ReactivityHuman,Mouse,Rat
• Immunogen DescriptionRecombinant fusion protein of human SPG7 (NP_003110.1).
• Alternative Names    SPG7; CAR; CMAR; PGN; SPG5C; paraplegin
• Accession No. Swiss-Prot#:Q9UQ90
  NCBI Gene ID:6687
• UniprotQ9UQ90
• Gene ID6687;
• Calculated MW 88kDa
• Formulation Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
• Storage Store at -20˚C

• WB 1:1000 - 1:2000
  IHC 1:50 - 1:200

This gene encodes a mitochondrial metalloprotease protein that is a member of the AAA family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Mutations in this gene cause autosomal recessive spastic paraplegia 7. Two transcript variants encoding distinct isoforms have been identified.

• Western blot analysis of extracts of various cell lines, using SPG7 at 1:1000 dilution.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting