• Product NameEXOSC1 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB
• Species ReactivityHuman
• Immunogen DescriptionRecombinant fusion protein of human EXOSC1 (NP_057130.1).
• Alternative Names    EXOSC1; CGI-108; CSL4; Csl4p; SKI4; Ski4p; p13; exosome component 1
• Accession No. Swiss-Prot#:Q9Y3B2
  NCBI Gene ID:51013
• UniprotQ9Y3B2
• Gene ID51013;
• Calculated MW 21kDa
• Formulation Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
• Storage Store at -20˚C

• WB 1:500 - 1:2000

This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. Alternative splicing of this gene results in multiple transcript variants.

• Western blot analysis of extracts of various cell lines, using EXOSC1 at 1:1000 dilution.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting