• Product NameSPG11 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB
• Species ReactivityHuman
• Immunogen DescriptionRecombinant fusion protein of human SPG11 (NP_079413.3).
• Alternative Names    SPG11; ALS5; CMT2X; KIAA1840; spatacsin
• Accession No. Swiss-Prot#:Q96JI7
  NCBI Gene ID:80208
• UniprotQ96JI7
• Gene ID80208;
• Calculated MW 280kDa
• Formulation Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
• Storage Store at -20˚C

• WB 1:200 - 1:2000

The protein encoded by this gene is a potential transmembrane protein that is phosphorylated upon DNA damage. Defects in this gene are a cause of spastic paraplegia type 11 (SPG11). Multiple transcript variants encoding different isoforms have been found for this gene.

• Western blot analysis of extracts of U-87MG cells, using SPG11 at 1:1000 dilution.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting