• Product NameIKB alpha Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB
• Species ReactivityHuman,Mouse,Rat
• Immunogen DescriptionRecombinant fusion protein of human IKB alpha (NP_065390.1).
• Alternative Names    NFKBIA; IKBA; MAD-3; NFKBI; NFKB inhibitor alpha
• Accession No. Swiss-Prot#:P25963
  NCBI Gene ID:4792
• UniprotP25963
• Gene ID4792;
• Calculated MW 36kDa
• Formulation Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
• Storage Store at -20˚C

• WB 1:500 - 1:2000
  IP 1:20 - 1:50

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

• Western blot analysis of extracts of various cell lines, using IKB alpha at 1:1000 dilution.
• Western blot analysis of extracts from normal (control) and IKB alpha knockout (KO) 293T cells, using IKB alpha at 1:1000 dilution.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting