• Product NameSPTLC2 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB
• Species ReactivityHuman,Mouse,Rat
• Immunogen DescriptionRecombinant fusion protein of human SPTLC2 (NP_004854.1).
• Alternative Names    SPTLC2; HSN1C; LCB2; LCB2A; NSAN1C; SPT2; hLCB2a; serine palmitoyltransferase 2
• Accession No. Swiss-Prot#:O15270
  NCBI Gene ID:9517
• UniprotO15270
• Gene ID9517;
• Calculated MW 58kDa
• Formulation Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
• Storage Store at -20˚C

• WB 1:500 - 1:2000

This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.

• Western blot analysis of extracts of various cell lines, using SPTLC2 at 1:3000 dilution.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting