• Product NameTrkB Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB
• Species ReactivityHuman,Mouse
• Immunogen DescriptionRecombinant fusion protein of human TrkB (NP_001007098.1).
• Alternative Names    NTRK2; GP145-TrkB; TRKB; trk-B; OBHD; BDNF/NT-3 growth factors receptor
• Accession No. Swiss-Prot#:Q16620
  NCBI Gene ID:4915
• UniprotQ16620
• Gene ID4915;
• Calculated MW 105kDa
• Formulation Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
• Storage Store at -20˚C

• WB 1:500 - 1:2000

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.

• Western blot analysis of extracts of various cell lines, using TrkB at 1:3000 dilution.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting