• Product NamePACS1 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB
• Species ReactivityHuman
• Immunogen DescriptionRecombinant fusion protein of human PACS1 (NP_060496.2).
• Alternative Names    PACS1; MRD17; SHMS; phosphofurin acidic cluster sorting protein 1
• Accession No. Swiss-Prot#:Q6VY07
  NCBI Gene ID:55690
• UniprotQ6VY07
• Gene ID55690;
• Calculated MW 105kDa
• Formulation Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
• Storage Store at -20˚C

• WB 1:1000 - 1:3000

This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance.

• Western blot analysis of extracts of 293T cells, using PACS1 at 1:3000 dilution.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting