• Product NameARR3 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB
• Species ReactivityMouse,Rat
• Immunogen DescriptionRecombinant fusion protein of human ARR3 (NP_004303.2).
• Alternative Names    ARR3; ARRX; cArr; arrestin-C
• Accession No. Swiss-Prot#:P36575
  NCBI Gene ID:407
• UniprotP36575
• Gene ID407;
• Calculated MW 42kDa
• Formulation Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
• Storage Store at -20˚C

• WB 1:500 - 1:2000

The protein encoded by this gene is a non-visual arrestin which binds to agonist-activated, phosphorylated G protein-coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein-coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma-tubulin to help regulate proper centrosome function.

• Western blot analysis of extracts of various cell lines, using ARR3 at 1:3000 dilution.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting