• Product NameHAUSP / USP7 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB,IHC,IF
• Species ReactivityHuman,Mouse,Rat
• Immunogen DescriptionRecombinant fusion protein of human HAUSP / USP7 (NP_003461.2).
• Alternative Names    USP7; HAUSP; TEF1; ubiquitin specific peptidase 7
• Accession No. Swiss-Prot#:Q93009
  NCBI Gene ID:7874
• UniprotQ93009
• Gene ID7874;
• Calculated MW 138kDa
• Formulation Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
• Storage Store at -20˚C

• WB 1:500 - 1:2000
  IHC 1:50 - 1:200
  IF 1:50 - 1:200

The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder.

• Immunohistochemistry of paraffin-embedded human kidney cancer using HAUSP / USP7 at dilution of 1:200 (40x lens).
• Immunohistochemistry of paraffin-embedded mouse heart using HAUSP / USP7 at dilution of 1:200 (40x lens).
• Immunofluorescence analysis of HeLa cells using HAUSP / USP7 .
• Western blot analysis of extracts of various cell lines, using HAUSP / USP7 at 1:1000 dilution.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting