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HECW1 Antibody #45953

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Datasheet PDF
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Catalog No. Package Size Price Quantity
50ul $219.00
100ul $319.00
Availability:Yes
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Description
  • Product NameHECW1 Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationImmunogen affinity purified
  • ApplicationsWB
  • Species ReactivityHu
  • SpecificityHECW1 Antibody detects endogenous levels of total HECW1
  • Immunogen TypePeptide
  • Immunogen DescriptionA synthesized peptide derived from human HECW1
  • Target NameHECW1
  • Alternative Names    KIAA0322, NEDL1
  • Accession No. Swiss-Prot#: Q76N89
    NCBI Gene ID:23072
  • UniprotQ76N89
  • Gene ID23072;
  • Calculated MW 180kDa
  • Concentration 1.0mg/mL
  • Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20˚C
Application Details

Published Papers

The E3 ubiquitin ligase HECW1 targets thyroid transcription factor 1 (TTF1/NKX2. 1) for its degradation in the ubiquitin-proteasome system. In Cell Signal on 2019 Jun by Jia Liu, Su Dong,et al..PMID: 30849519, , (2019),
PMID: 30849519
Two distinct E3 ligases, SCFFBXL19 and HECW1, degrade thyroid transcription factor 1 in normal thyroid epithelial and follicular thyroid carcinoma cells, respectively. In FASEB J on 2019 Sep by Jia Liu, Su Dong, et al..PMID: 31238008, , (2019),
PMID: 31238008
Please let us know if you have published research using #45953 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep