• Product NameUBR5 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB
• Species ReactivityHuman
• Immunogen DescriptionRecombinant fusion protein of human UBR5 (NP_056986.2).
• Alternative Names    UBR5; DD5; EDD; EDD1; HYD; E3 ubiquitin-protein ligase UBR5
• Accession No. Swiss-Prot#:O95071
  NCBI Gene ID:51366
• UniprotO95071
• Gene ID51366;
• Calculated MW 300kDa
• Formulation Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
• Storage Store at -20˚C

• WB 1:500 - 1:2000

This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation.

• Western blot analysis of extracts of various cell lines, using UBR5 at 1:3000 dilution.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting