• Product NamePLP1 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB
• Species ReactivityHuman,Mouse
• Immunogen DescriptionRecombinant fusion protein of human PLP1 (NP_955772.1).
• Alternative Names    PLP1; GPM6C; HLD1; MMPL; PLP; PLP/DM20; PMD; SPG2; proteolipid protein 1
• Accession No. Swiss-Prot#:P60201
  NCBI Gene ID:5354
• UniprotP60201
• Gene ID5354;
• Calculated MW 34kDa
• Formulation Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
• Storage Store at -20˚C

• WB 1:500 - 1:2000

This gene encodes a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively splicing results in multiple transcript variants, including the DM20 splice variant.

• Western blot analysis of extracts of various cell lines, using PLP1 at 1:3000 dilution.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting