• Product NameERLIN1 Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB,IHC
• Species ReactivityHuman,Mouse,Rat
• Immunogen DescriptionRecombinant fusion protein of human ERLIN1 (NP_006450.2).
• Alternative Names    ERLIN1; C10orf69; Erlin-1; KE04; KEO4; SPFH1; SPG62; erlin-1
• Accession No. Swiss-Prot#:O75477
  NCBI Gene ID:10613
• UniprotO75477
• Gene ID10613;
• Calculated MW 39kDa
• Formulation Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
• Storage Store at -20˚C

• WB 1:500 - 1:2000
  IHC 1:50 - 1:200

The protein encoded by this gene is part of a protein complex that mediates degradation of inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway, which promotes cellular cholesterol homeostasis. Defects in this gene have been associated with spastic paraplegia 62.

• Western blot analysis of extracts of various cell lines, using ERLIN1 at 1:1000 dilution.
• Immunohistochemistry of paraffin-embedded human appendix using ERLIN1 at dilution of 1:100 (40x lens).
• Immunohistochemistry of paraffin-embedded human colon using ERLIN1 at dilution of 1:100 (40x lens).
• Immunohistochemistry of paraffin-embedded human gastric cancer using ERLIN1 at dilution of 1:100 (40x lens).
• Immunohistochemistry of paraffin-embedded human liver cancer using ERLIN1 at dilution of 1:100 (40x lens).
• Immunohistochemistry of paraffin-embedded human placenta using ERLIN1 at dilution of 1:100 (40x lens).
• Immunohistochemistry of paraffin-embedded human stomach using ERLIN1 at dilution of 1:100 (40x lens).

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting