• Product NameGUCA1A Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB,IHC
• Species ReactivityMouse
• Immunogen DescriptionRecombinant fusion protein of human GUCA1A (NP_000400.2).
• Alternative Names    GUCA1A; C6orf131; COD3; CORD14; GCAP; GCAP1; GUCA; GUCA1; guanylate cyclase activator 1A
• Accession No. Swiss-Prot#:P43080
  NCBI Gene ID:2978
• UniprotP43080
• Gene ID2978;
• Calculated MW Refer to figures
• Formulation Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
• Storage Store at -20˚C

• WB 1:500 - 1:2000
  IHC 1:50 - 1:200

This gene encodes an enzyme that plays a role in the recovery of retinal photoreceptors from photobleaching. This enzyme promotes the activity of retinal guanylyl cyclase-1 (GC1) at low calcium concentrations and inhibits GC1 at high calcium concentrations. Mutations in this gene can cause cone dystrophy 3 and code-rod dystrophy 14. Alternative splicing results in multiple transcript variants.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting