• Product NameBCHE Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total BCHE protein.
• Immunogen Typepeptide
• Immunogen DescriptionSynthetic protein corresponding to residues near the C terminal of human BCHE
• Target NameBCHE
• Alternative Names    E1; CHE1; CHE2
• Accession No. Swiss-Prot:P06276
  NCBI Gene ID:590
  NCBI Protein:BC008396
• UniprotP06276
• Gene ID590;
• Concentration 1.4mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1: 50-300

Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.

• The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 46340(BCHE Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200)

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting