• Product NameC21orf2 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total C21orf2 protein.
• Immunogen Typepeptide
• Immunogen DescriptionSynthetic protein corresponding to residues near the C terminal of human C21orf2
• Target NameC21orf2
• Alternative Names    LRRC76; YF5/A2
• Accession No. Swiss-Prot:O43822
  NCBI Gene ID:755
  NCBI Protein:BC031300
• UniprotO43822
• Gene ID755;
• Concentration 0.9mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1: 25-100

Four alternatively spliced transcript variants encoding four different isoforms have been found for this nuclear gene. All isoforms contain leucine-rich repeats. Three of these isoforms are mitochondrial proteins and one of them lacks the target peptide, so is not located in mitochondrion. This gene is down-regulated in Down syndrome (DS) brain, which may represent mitochondrial dysfunction in DS patients.?

• The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 46369(C21orf2 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: x200)
• The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 46369(C21orf2 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: x200)

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting