• Product NameCLN5 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification
• ApplicationsWB IHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total CLN5 protein.
• Immunogen Typepeptide
• Immunogen DescriptionSynthetic peptide corresponding to internal residues of human CLN5
• Target NameCLN5
• Alternative Names    NCL
• Accession No. Swiss-Prot:O75503
  NCBI Gene ID:1203
  NCBI Protein:NP_006484
• UniprotO75503
• Gene ID1203;
• Calculated MW 41 kDa
• Concentration 2.5mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:200-1:1000
  Immunohistochemistry: 1: 40-200

This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.

• Gel: 8%SDS-PAGE
  lysate: 40 ¦Ìg, Lane: 231 cell lysate,
  Primary antibody: 46515£¨CLN5 Antibody) at dilution 1/250
  Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,
  Exposure time: 10 minutes
• The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 46515(CLN5 Antibody) at dilution 1/65, on the right is treated with synthetic peptide. (Original magnification: x200)

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting