• Product NameCNGA4 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total CNGA4 protein.
• Immunogen Typepeptide
• Immunogen DescriptionSynthetic peptide corresponding to residues near the C terminal of human CNGA4
• Target NameCNGA4
• Alternative Names    CNG4; CNG5; CNCA2; CNG-4; CNGB2; OCNC2; OCNCb; OCNCBETA
• Accession No. Swiss-Prot:Q8IV77
  NCBI Gene ID:1262
  NCBI Protein:NP_001032406
• UniprotQ8IV77
• Gene ID1262;
• Calculated MW 66 kDa
• Concentration 0.7mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:200-1:1000

Second messenger, cAMP, causes the opening of cation-selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection.

• Gel: 8%SDS-PAGE
  lysate: 40 ¦Ìg, Lane 1-2: Human cerebella tissue and Human cerebrum tissue lysates,
  Primary antibody: 46522£¨CNGA4 Antibody) at dilution 1/300
  Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,
  Exposure time: 5 seconds

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting