• Product NameXPO1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification
• ApplicationsWB IHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total XPO1 protein.
• Immunogen Typepeptide
• Immunogen DescriptionSynthetic peptide corresponding to residues near the C terminal of human XPO1
• Target NameXPO1
• Alternative Names    emb; CRM1; exp1
• Accession No. Swiss-Prot:O14980
  NCBI Gene ID:7514
  NCBI Protein:NP_003391
• UniprotO14980
• Gene ID7514;
• Calculated MW 123 kDa
• Concentration 1.6mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500-1:2000
  Immunohistochemistry: 1: 30-150

This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.

• Gel: 6%SDS-PAGE
  , Lysate: 40 ¦Ìg, Lane 1-3: Hela,K562 and HEPG2 cell lysates,
  Primary antibody: 46711(XPO1 Antibody) at dilution 1/200,
  Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,
  Exposure time: 10 seconds
• The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using 46711(XPO1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200)
• The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 46711(XPO1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200)

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting