• Product NameCALR Conjugated Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Species ReactivityHu Ms Rt
• SpecificityThe antibody detects endogenous levels of total CALR protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human CALR.
• Excitation EmissionAF350: 346nm/442nm
  AF405: 401nm/421nm
  AF488: 493nm/519nm
  AF555: 555nm/565nm
  AF594: 591nm/614nm
  AF647: 651nm/667nm
  AF680: 679nm/702nm
  AF750: 749nm/775nm
• Target NameCALR
• Alternative Names    CALR; CRP55; CRTC; Calreticulin precursor; ERp60
• Accession No. Swiss-Prot: P27797
  NCBI Gene ID: 811
• SDS-PAGE MW 48kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  Immunohistochemistry: 1:50~1:100
  Immunofluorescence: 1:100~1:500

Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis By similarity.

McCauliffe D.P., J. Clin. Invest. 85:1379-1391(1990).
Rokeach L.A., J. Immunol. 147:3031-3039(1991).
McCauliffe D.P., J. Biol. Chem. 267:2557-2562(1992).

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting