• Product NameOPA1 Rabbit Polyclonal Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• IsotypeIgG
• PurificationAffinity purification
• ApplicationsWB,IHC,IF
• Species ReactivityHuman,Mouse,Rat
• Immunogen DescriptionRecombinant fusion protein of human OPA1 (NP_056375.2).
• Alternative Names    OPA1;BERHS;MGM1;MTDPS14;NPG;NTG;largeG
• Accession No. Uniprot:O60313
  GeneID:4976
• UniprotO60313
• Gene ID4976
• Calculated MW 111kDa/115kDa
• SDS-PAGE MW 80KDa
• Formulation PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Storage Store at -20˚C. Avoid freeze / thaw cycles.

• WB 1:500 - 1:2000
  IHC 1:50 - 1:200
  IF 1:50 - 1:200

This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.

• Western blot analysis of extracts of various cell lines, using OPA1 antibody.
• Immunohistochemistry of paraffin-embedded Rat kidney using OPA1 antibody.
• Immunohistochemistry of paraffin-embedded Mouse heart using OPA1 antibody.
• Immunohistochemistry of paraffin-embedded Rat heart using OPA1 antibody.
• Immunohistochemistry of paraffin-embedded Mouse brain using OPA1 antibody.
• Immunofluorescence analysis of NIH-3T3 cells using OPA1 antibody at dilution of 1:100 . Blue: DAPI for nuclear staining.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting