• Product NameTuberin (phospho Tyr1571) Polyclonal Antibody
• Host SpeciesRabbit
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB,IHC-p,IF(paraffin section),ELISA
• Species ReactivityHuman,Mouse,Rat
• SpecificityPhospho-Tuberin (Y1571) Polyclonal Antibody detects endogenous levels of Tuberin protein only when phosphorylated at Y1571.
• Immunogen DescriptionThe antiserum was produced against synthesized peptide derived from human TSC2 around the phosphorylation site of Tyr1571. AA range:1537-1586
• Alternative Names    TSC2; TSC4; Tuberin; Tuberous sclerosis 2 protein
• Accession No. Swiss Prot:P49815
  GeneID:7249
• UniprotP49815
• Gene ID7249
• SDS-PAGE MW 170
• Concentration 1 mg/ml
• Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Storage -20˚C/1

• Western Blot: 1/500 - 1/2000.
  Immunohistochemistry: 1/100 - 1/300.
  ELISA: 1/5000. Not yet tested in other applications.

tuberous sclerosis 2(TSC2) Homo sapiens Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting