• Product NameTBK1/NAK (phospho-Ser172) rabbit pAb
• Host SpeciesRabbit
• PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
• ApplicationsWB
• Species ReactivityHuman,Mouse
• SpecificityThis antibody detects endogenous levels of Human Mouse TBK1/NAK (phospho-Ser172)
• Immunogen DescriptionSynthesized phosho peptide around human TBK1 and NAK (Ser172)
• Alternative Names    Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)
• Accession No. Swiss Prot:Q9UHD2
  GeneID:29110
• UniprotQ9UHD2
• Gene ID29110
• SDS-PAGE MW 80
• Concentration 1 mg/ml
• Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Storage -20˚C/1

• WB 1:1000-2000

TANK binding kinase 1(TBK1) Homo sapiens The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010],

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting