• Product NameLAT (phospho-Tyr171) rabbit pAb
• Host SpeciesRabbit
• PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
• ApplicationsWB
• Species ReactivityHuman
• SpecificityThis antibody detects endogenous levels of Human LAT (phospho-Tyr171)
• Immunogen DescriptionSynthesized phosho peptide around human LAT (Tyr171)
• Alternative Names    Linker for activation of T-cells family member 1 (36 kDa phospho-tyrosine adapter protein) (pp36) (p36-38)
• Accession No. Swiss Prot:O43561
  GeneID:27040
• UniprotO43561
• Gene ID27040
• SDS-PAGE MW 34
• Concentration 1 mg/ml
• Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Storage -20˚C/1

• WB 1:1000-2000

linker for activation of T-cells(LAT) Homo sapiens The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting