• Product NameBAP1 (phospho-Ser592) rabbit pAb
• Host SpeciesRabbit
• PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
• ApplicationsWB
• Species ReactivityHuman
• SpecificityThis antibody detects endogenous levels of Human BAP1 (phospho-Ser592)
• Immunogen DescriptionSynthesized phosho peptide around human BAP1 (Ser592)
• Alternative Names    Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1-associated protein 1) (Cerebral protein 6)
• Accession No. Swiss Prot:Q92560
  GeneID:8314
• UniprotQ92560
• Gene ID8314
• SDS-PAGE MW 80
• Concentration 1 mg/ml
• Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Storage -20˚C/1

• WB 1:1000-2000

BRCA1 associated protein 1(BAP1) Homo sapiens This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. [provided by RefSeq, May 2013],

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting