• Product NameRecombinant human IL38
• Host SpeciesHEK293
• Purification> 95% by Tris-Bis PAGE;> 95% by SEC-HPLC
• Endotoxin< 1 EU/μg of the protein by LAL method.
• Immunogen DescriptionA7-W152
• Target NameIL38
• Alternative Names    Interleukin-1 family member 10
• Accession No. Uniprot:Q8WWZ1
  Gene ID:84639
• UniprotQ8WWZ1
• Gene ID84639
• Target Species human
• Calculated MW 17.0 Kda
• Tag Info addtional amino acid free
• Formulation 0.22 μm filtered solution of PBS, pH 7.4.
• Reconstitution 0.2 mg/mL in sterile PBS, pH7.4
• Storage Aliquot and store at -80˚C. Avoid repeated freeze/thaw cycles.

Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting